RT Journal Article
T1 Multidisciplinary Management of the Adverse Effects of Apremilast.
T2 Manejo de los efectos adversos de apremilast desde un abordaje multidisciplinar.
A1 Daudén Tello, E
A1 Alonso Suárez, J
A1 Beltrán Catalán, E
A1 Blasco Maldonado, C
A1 Herrero Manso, M C
A1 Jiménez Morales, A
A1 Marín-Jiménez, I
A1 Martín-Arranz, M D
A1 García-Merino, A
A1 Porta Etessam, J
A1 Rodríguez-Sagrado, M A
A1 Rosas Gómez de Salazar, J
A1 Trujillo Martín, E
A1 Salgado-Boquete, L
K1 Adverse effects
K1 Apremilast
K1 Cefalea
K1 Diarrea
K1 Diarrhea
K1 Efectos adversos
K1 Headache
K1 Nausea
K1 Náuseas
K1 Psoriasis
AB We present a series of general and specific recommendations based on pathophysiologic considerations for managing the most common adverse effects of apremilast that lead to treatment discontinuation: diarrhea, nausea, and headache. The recommendations are based on a review of the literature and the experience of a multidisciplinary team of 14 experts including dermatologists, rheumatologists, neurologists, gastroenterologists, pharmacists, and nurses. We propose a series of simple algorithms that include clinical actions and suggestions for pharmacologic treatment. The adverse effects of apremilast can be managed from a multidisciplinary approach. The purpose of optimizing management is to bring clinical benefits to patients.
YR 2020
FD 2020-09-07
LK http://hdl.handle.net/10668/16239
UL http://hdl.handle.net/10668/16239
LA en
LA es
DS RISalud
RD Apr 19, 2025