RT Journal Article
T1 Nonalcoholic Steatohepatitis Is the Fastest Growing Cause of Hepatocellular Carcinoma in Liver Transplant Candidates.
A1 Younossi, Zobair
A1 Stepanova, Maria
A1 Ong, Janus P
A1 Jacobson, Ira M
A1 Bugianesi, Elisabetta
A1 Duseja, Ajay
A1 Eguchi, Yuichiro
A1 Wong, Vincent W
A1 Negro, Francesco
A1 Yilmaz, Yusuf
A1 Romero-Gomez, Manuel
A1 George, Jacob
A1 Ahmed, Aijaz
A1 Wong, Robert
A1 Younossi, Issah
A1 Ziayee, Mariam
A1 Afendy, Arian
A1 Global Nonalcoholic Steatohepatitis Council, 
K1 Liver Cancer
K1 Mortality
K1 NAFLD
K1 OPTN
K1 Transplant Waitlist
K1 UNOS
AB Although hepatitis B and C have been the main drivers of hepatocellular carcinoma (HCC), nonalcoholic steatohepatitis (NASH) has recently become an important cause of HCC. The aim of this study was to assess the causes of HCC among liver transplant (LT) candidates in the United States. The Scientific Registry of Transplant Recipients (2002-2016) was used to estimate the trends in prevalence of HCC in LT candidates with the most common types of chronic liver disease: alcoholic liver disease (ALD), chronic hepatitis B (CHB), chronic hepatitis C, and NASH. 158,347 adult LT candidates were included. Of these, 26,121 (16.5%) had HCC; this proportion increased from 6.4% (2002) to 23.0% (2016) (trend P  .10), the proportion of CHB decreased 3.1-fold (P  .05). Nonalcoholic steatohepatitis is the most rapidly growing cause of HCC among US patients listed for liver transplantation.
YR 2018
FD 2018-06-14
LK http://hdl.handle.net/10668/12602
UL http://hdl.handle.net/10668/12602
LA en
DS RISalud
RD Apr 10, 2025