TY - JOUR AU - Ortega-Saenz, Patricia AU - Macias, David AU - Levitsky, Konstantin L. AU - Rodriguez-Gomez, Jose A. AU - Gonzalez-Rodriguez, Patricia AU - Bonilla-Henao, Victoria AU - Arias-Mayenco, Ignacio AU - Lopez-Barneo, Jose PY - 2016 DO - 10.1113/JP272961 SN - 0022-3751 UR - http://hdl.handle.net/10668/18996 T2 - Journal of physiology-london AB - Biotin, a vitamin whose main role is as a coenzyme for carboxylases, accumulates at unusually large amounts within cells of the carotid body (CB). In biotin-deficient rats biotin rapidly disappears from the blood; however, it remains at relatively... LA - en PB - Wiley-blackwell KW - arterial chemoreceptors KW - biotin KW - carotid body KW - Basal ganglia disease KW - Multiple carboxylase deficiency KW - Blood-brain-barrier KW - Glomus cells KW - Asialoglycoprotein receptor KW - Transporter family KW - Chromaffin cells KW - Hypoxia KW - Mechanisms KW - Inhibition TI - Selective accumulation of biotin in arterial chemoreceptors: requirement for carotid body exocytotic dopamine secretion TY - research article VL - 594 ER -