TY - JOUR AU - Ortega-Saenz, Patricia AU - Macias, David AU - Levitsky, Konstantin L. AU - Rodriguez-Gomez, Jose A. AU - Gonzalez-Rodriguez, Patricia AU - Bonilla-Henao, Victoria AU - Arias-Mayenco, Ignacio AU - Lopez-Barneo, Jose PY - 2016 DO - 10.1113/JP272961 SN - 0022-3751 UR - http://hdl.handle.net/10668/18996 T2 - Journal of physiology-london AB - Biotin is a water-soluble vitamin required for the function of carboxylases as well as for the regulation of gene expression. Here, we report that biotin accumulates in unusually large amounts in cells of arterial chemoreceptors, carotid body (CB) and... LA - en PB - Wiley-blackwell KW - arterial chemoreceptors KW - biotin KW - carotid body KW - Basal ganglia disease KW - Multiple carboxylase deficiency KW - Blood-brain-barrier KW - Glomus cells KW - Asialoglycoprotein receptor KW - Transporter family KW - Chromaffin cells KW - Hypoxia KW - Mechanisms KW - Inhibition KW - Vesicular Monoamine Transport Proteins KW - Carotid Body KW - biotin transporter KW - Tetrabenazine KW - Homeostasis TI - Selective accumulation of biotin in arterial chemoreceptors: requirement for carotid body exocytotic dopamine secretion TY - research article VL - 594 ER -