RT Journal Article
T1 High Rates of SARS-CoV-2 Family Transmission in Children of Healthcare Workers During the First Pandemic Wave in Madrid, Spain: Serologic Study.
A1 Méndez-Echevarría, Ana
A1 Sainz, Talía
A1 de Felipe, Beatriz
A1 Alcolea, Sonia
A1 Olbrich, Peter
A1 Goycochea-Valdivia, Walter A
A1 Escosa-García, Luis
A1 Cobo, Lorena
A1 Calvo, Cristina
A1 Neth, Olaf
AB Data on SARS-CoV-2 transmission among children living with healthcare workers (HCWs) are scarce. A cross-sectional study was performed at a tertiary Hospital in Madrid, including children of HCW who suffered from SARS-CoV-2 infection between March and May 2020. Children underwent enzyme-linked immunosorbent serological study for detecting SARS-CoV-2 antibodies: VIRCELL IgG assay. One hundred thirteen children from 69 HCWs with confirmed SARS-CoV-2 infection were recruited: 47 children had positive IgG (41.6%). Children secondary attack rate was 43.7% (25% if both parents have had asymptomatic infection; 39.5% if one parent was symptomatic; and 47% when both parents had symptoms). Having a positive sibling was associated with a positive IgG result (odds ratio = 12.2; 95% confidence interval: 4.4-33.7, P  We observed a very high SARS-CoV-2 transmission in children of HCW during the first pandemic wave, especially when both parents were symptomatic. Having a positive sibling was associated with seroconversion, supporting the important role of family clusters in the transmission of SARS-CoV-2.
YR 2021
FD 2021
LK http://hdl.handle.net/10668/17187
UL http://hdl.handle.net/10668/17187
LA en
DS RISalud
RD Apr 8, 2025