RT Journal Article
T1 Real-World Outcomes Using a Spinal Cord Stimulation Device Capable of Combination Therapy for Chronic Pain: A European, Multicenter Experience.
A1 Kallewaard, Jan Willem
A1 Paz-Solis, Jose Francisco
A1 De Negri, Pasquale
A1 Canós-Verdecho, Maria Angeles
A1 Belaid, Hayat
A1 Thomson, Simon J
A1 Abejón, David
A1 Vesper, Jan
A1 Mehta, Vivek
A1 Rigoard, Philippe
A1 Maino, Paolo
A1 Love-Jones, Sarah
A1 Peña, Isaac F
A1 Bayerl, Simon
A1 Perruchoud, Christophe
A1 Bougeard, Renaud
A1 Mertz, Cleo
A1 Pei, Yu
A1 Jain, Roshini
K1 SCS
K1 chronic pain
K1 combination therapy
K1 customized stimulation field targeting
K1 spinal cord stimulation
AB Given the differing mechanisms thought to underlie therapeutic sub- and supra-perception-based neurostimulative modalities, Spinal Cord Stimulation (SCS) systems designed for combined delivery of these approaches may help improve analgesic outcomes and quality of life, and reduce treatment failures. This multicenter, observational case-series evaluated 188 patients with chronic back and/or leg pain implanted with an SCS device capable of sequential or simultaneous delivery of sub-perception and supra-perception stimulation programming (i.e., combination therapy) at 16 in Europe. Following implantation, patients were provided with an array of advanced supra-perception programs (e.g., paresthesia-based SCS using multiple independent current sources), and a custom set of sub-perception programs optimized with specific waveforms and/or field shapes. A mean overall pain score of 7.9 ± 1.7 (Standard Deviation (SD)) was reported pre-trial (Baseline). Overall pain was reduced by 4.4 ± 2.8 points (NRS) at 3-months (n = 117) and at 12 months post-implant (n = 90), respectively (p
SN 2077-0383
YR 2021
FD 2021-09-10
LK https://hdl.handle.net/10668/27357
UL https://hdl.handle.net/10668/27357
LA en
DS RISalud
RD Apr 8, 2025