TY - JOUR AU - Sixto-López, Yudibeth AU - Gómez-Vidal, José Antonio AU - de Pedro, Nuria AU - Bello, Martiniano AU - Rosales-Hernández, Martha Cecilia AU - Correa-Basurto, José PY - 2020 DO - 10.1038/s41598-020-67112-4 UR - http://hdl.handle.net/10668/15838 T2 - Scientific reports AB - Histone deacetylases (HDACs) belong to a family of enzymes that remove acetyl groups from the ɛ-amino of histone and nonhistone proteins. Additionally, HDACs participate in the genesis and development of cancer diseases as promising therapeutic... LA - en KW - Antineoplastic Agents KW - Breast Neoplasms KW - Carcinoma, Hepatocellular KW - Cell Line, Tumor KW - Cell Proliferation KW - Drug Design KW - Drug Screening Assays, Antitumor KW - Female KW - Hep G2 Cells KW - Histone Deacetylase 1 KW - Histone Deacetylase 6 KW - Histone Deacetylase Inhibitors KW - Histone Deacetylases KW - Humans KW - Hydroxamic Acids KW - Liver Neoplasms KW - MCF-7 Cells KW - Molecular Docking Simulation KW - Repressor Proteins TI - Hydroxamic acid derivatives as HDAC1, HDAC6 and HDAC8 inhibitors with antiproliferative activity in cancer cell lines. TY - research article VL - 10 ER -