TY - JOUR AU - Olmo, Francisco AU - Costas, Miquel AU - Marin, Clotilde AU - Rosales, Maria Jose AU - Martin-Escolano, Ruben AU - Cusso, Olaf AU - Gutierrez-Sanchez, Ramon AU - Ribas, Xavi AU - Sanchez-Moreno, Manuel PY - 2016 DO - 10.1080/1120009X.2016.1190536 UR - http://hdl.handle.net/10668/10143 T2 - Journal of chemotherapy (Florence, Italy) AB - A series of tetraamine-based compounds was prepared, and their trypanocidal effects against Trypanosoma cruzi and cytotoxicity were determined through the determination of IC50 values. In vivo assays were performed in mice, where parasitaemia levels... LA - en PB - Taylor & Francis KW - American trypanosomiasis KW - Chemotherapy KW - Murine model KW - Tetradentate polyamines KW - Animals KW - Chagas Disease KW - Disease Models, Animal KW - Female KW - Mice KW - Mice, Inbred BALB C KW - Organometallic Compounds KW - Polyamines KW - Trypanosoma cruzi TI - Tetradentate polyamines as efficient metallodrugs for Chagas disease treatment in murine model. TY - research article VL - 29 ER -