TY - JOUR AU - Sanchez-Martin, Victoria AU - Lopez-Pujante, Carmen AU - Soriano-Rodriguez, Miguel AU - Garcia-Salcedo, Jose A. PY - 2020 DO - 10.3390/ijms21238900 UR - http://hdl.handle.net/10668/3653 T2 - International Journal of Molecular Sciences AB - Non-canonical, four-stranded nucleic acids secondary structures are present within regulatory regions in the human genome and transcriptome. To date, these quadruplex structures include both DNA and RNA G-quadruplexes, formed in guanine-rich... LA - en PB - MDPI KW - DNA G-quadruplex KW - RNA G-quadruplex KW - i-Motif KW - Cancer KW - G-Cuádruplex KW - Neoplasias KW - Ácidos nucleicos KW - Citosina KW - ADN KW - Guanina KW - Oncogenes KW - Telómero KW - Medical Subject Headings::Chemicals and Drugs::Heterocyclic Compounds::Heterocyclic Compounds, 1-Ring::Pyrimidines::Pyrimidinones::Cytosine KW - Medical Subject Headings::Chemicals and Drugs::Nucleic Acids, Nucleotides, and Nucleosides::Nucleic Acids::DNA KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Processes::Gene Expression Regulation::Gene Expression Regulation, Neoplastic KW - Medical Subject Headings::Chemicals and Drugs::Heterocyclic Compounds::Heterocyclic Compounds, 2-Ring::Purines::Purinones::Hypoxanthines::Guanine KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans KW - Medical Subject Headings::Diseases::Neoplasms KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Structures::Genome::Genome Components::Genes::Genes, Neoplasm::Oncogenes KW - Medical Subject Headings::Anatomy::Cells::Cellular Structures::Intracellular Space::Cell Nucleus::Cell Nucleus Structures::Intranuclear Space::Chromosomes::Chromosome Structures::Telomere KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Neoplasm Proteins::Tumor Suppressor Proteins KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Structures::Nucleic Acid Conformation::G-Quadruplexes KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Drug Therapy::Molecular Targeted Therapy TI - An Updated Focus on Quadruplex Structures as Potential Therapeutic Targets in Cancer TY - review article ER -