RT Journal Article
T1 CORonary Diet Intervention with Olive oil and cardiovascular PREVention study (the CORDIOPREV study): Rationale, methods, and baseline characteristics: A clinical trial comparing the efficacy of a Mediterranean diet rich in olive oil versus a low-fat diet on cardiovascular disease in coronary patients.
A1 Delgado-Lista, Javier
A1 Perez-Martinez, Pablo
A1 Garcia-Rios, Antonio
A1 Alcala-Diaz, Juan F
A1 Perez-Caballero, Ana I
A1 Gomez-Delgado, Francisco
A1 Fuentes, Francisco
A1 Quintana-Navarro, Gracia
A1 Lopez-Segura, Fernando
A1 Ortiz-Morales, Ana M
A1 Delgado-Casado, Nieves
A1 Yubero-Serrano, Elena M
A1 Camargo, Antonio
A1 Marin, Carmen
A1 Rodriguez-Cantalejo, Fernando
A1 Gomez-Luna, Purificacion
A1 Ordovas, Jose M
A1 Lopez-Miranda, Jose
A1 Perez-Jimenez, Francisco
K1 Cardiovascular diseases
K1 Cholesterol, LDL
K1 Comorbidity
K1 Coronary disease
K1 Diet, fat-restricted
AB Coronary heart disease (CHD) represents a major global health burden. However, despite the well-known influence that dietary habits exert over the progression of this disease, there are no well-established and scientifically sound dietary approaches to prevent the onset of clinical outcomes in secondary prevention. The objective of the CORonary Diet Intervention with Olive oil and cardiovascular PREVention study (CORDIOPREV study, clinical trials number NCT00924937) is to compare the ability of a Mediterranean diet rich in virgin olive oil versus a low-fat diet to influence the composite incidence of cardiovascular events after 7 years in subjects with documented CHD at baseline. For this purpose, we enrolled 1,002 coronary patients from Spain. Baseline assessment (2009-2012) included detailed interviews and measurements to assess dietary, social, and biological variables. Results of baseline characteristics: The CORDIOPREV study in Spain describes a population with a high body mass index (37.2% overweight and 56.3% obesity) and with a median of low-density lipoprotein cholesterol of 88.5 mg/dL (70.6% of the patients having  b100 mg/dL and 20.3% patients b70 mg/dL). A total of 9.6% of the participants were active smokers, and 64.4% were former smokers. Metabolic syndrome was present in 58% of this population. To sum up, we describe here the rationale, methods, and baseline characteristics of the CORDIOPREV study, which will test for the first time the efficacy of a Mediterranean diet rich in extra virgin olive oil as compared with a low-fat diet on the incidence of CHD recurrence in a longterm follow-up study. (Am Heart J 2016;177:42-50.)
PB Elsevier
YR 2016
FD 2016-04-22
LK http://hdl.handle.net/10668/10174
UL http://hdl.handle.net/10668/10174
LA en
NO Delgado-Lista J, Perez-Martinez P, Garcia-Rios A, Alcala-Diaz JF, Perez-Caballero AI, Gomez-Delgado F, et al. CORonary Diet Intervention with Olive oil and cardiovascular PREVention study (the CORDIOPREV study): Rationale, methods, and baseline characteristics: A clinical trial comparing the efficacy of a Mediterranean diet rich in olive oil versus a low-fat diet on cardiovascular disease in coronary patients. Am Heart J. 2016 Jul;177:42-50
DS RISalud
RD Apr 11, 2025