RT Journal Article
T1 SEOM Clinical Guideline of management of soft-tissue sarcoma (2020).
A1 de Juan Ferré, A
A1 Álvarez Álvarez, R
A1 Casado Herráez, A
A1 Cruz Jurado, J
A1 Estival González, A
A1 Martín-Broto, J
A1 Martínez Marín, V
A1 Moreno Vega, A
A1 Sebio García, A
A1 Valverde Morales, C
K1 Guidelines
K1 Sarcoma
K1 Soft-tissue tumors
K1 Uncommon tumors
AB Soft-tissue sarcomas constitute an uncommon and heterogeneous group of tumors of mesenchymal origin. Diagnosis, treatment, and management should be performed by an expert multidisciplinary team. MRI/CT of the primary tumor and biopsy is mandatory before any treatment. Wide surgical resection with tumor-free tissue margin is the mainstay for localized disease. Radiotherapy is indicated in large, deep, high-grade tumors, or after marginal resection not suitable for re-excision. Perioperative chemotherapy should be discussed for high-risk sarcomas of the extremities and trunk-wall. In the case of oligometastatic disease, patients should be considered for local therapies. First-line treatment with anthracyclines (or in combination with ifosfamide) is the treatment of choice. Other drugs have shown activity in second-line therapy and in specific histological subtypes but options are limited and thus, a clinical trial should always be discussed.
YR 2021
FD 2021-01-06
LK http://hdl.handle.net/10668/16929
UL http://hdl.handle.net/10668/16929
LA en
DS RISalud
RD Apr 6, 2025