RT Journal Article
T1 Oral Mucositis: Melatonin Gel an Effective New Treatment.
A1 Abdel Moneim, Ahmed Esmat
A1 Guerra-Librero, Ana
A1 Florido, Javier
A1 Shen, Ying-Qiang
A1 Fernandez-Gil, Beatriz
A1 Acuña-Castroviejo, Darío
A1 Escames, Germaine
K1 chemotherapy
K1 management
K1 melatonin
K1 mucositis
K1 pathophysiology
K1 radiotherapy
AB The current treatment for cervico-facial cancer involves radio and/or chemotherapy. Unfortunately, cancer therapies can lead to local and systemic complications such as mucositis, which is the most common dose-dependent complication in the oral cavity and gastrointestinal tract. Mucositis can cause a considerably reduced quality of life in cancer patients already suffering from physical and psychological exhaustion. However, the role of melatonin in the treatment of mucositis has recently been investigated, and offers an effective alternative therapy in the prevention and/or management of radio and/or chemotherapy-induced mucositis. This review focuses on the pathobiology and management of mucositis in order to improve the quality of cancer patients' lives.
PB MDPI AG
YR 2017
FD 2017-05-03
LK http://hdl.handle.net/10668/11181
UL http://hdl.handle.net/10668/11181
LA en
NO Abdel Moneim AE, Guerra-Librero A, Florido J, Shen YQ, Fernández-Gil B, Acuña-Castroviejo D, et al. Oral Mucositis: Melatonin Gel an Effective New Treatment. Int J Mol Sci. 2017 May 7;18(5):1003.
NO Part of this study was partially funded by the following grants: SAF2009-14037 from the Spanish Ministry of Economy and Competitivity (MINECO), CB/10/00238 from the Carlos III Health Institute, GREIB.PT_2010_04 from the CEIBiotic Program of the University of Granada, Spain, and CTS-101 from the Innovation, Science, and Business Council, Junta de Andalucía, Spain. Finally, we wish to thank Michael O’Shea for proofreading the paper.
DS RISalud
RD Apr 20, 2025