TY - JOUR AU - Benito, José M AU - Ortiz, María C AU - León, Agathe AU - Sarabia, Luis A AU - Ligos, José M AU - Montoya, María AU - Garcia, Marcial AU - Ruiz-Mateos, Ezequiel AU - Palacios, Rosario AU - Cabello, Alfonso AU - Restrepo, Clara AU - Rodriguez, Carmen AU - Del Romero, Jorge AU - Leal, Manuel AU - Muñoz-Fernández, María A AU - Alcamí, José AU - García, Felipe AU - Górgolas, Miguel AU - Rallón, Norma AU - ECRIS integrated in the Spanish AIDS Research Network PY - 2018 DO - 10.1186/s12916-018-1026-6 UR - http://hdl.handle.net/10668/12193 T2 - BMC medicine AB - Despite long-lasting HIV replication control, a significant proportion of elite controller (EC) patients may experience CD4 T-cell loss. Discovering perturbations in immunological parameters could help our understanding of the mechanisms that may be... LA - en KW - CD4 T-cell loss KW - CD8 exhaustion KW - Class modeling KW - Elite controllers KW - T-cell homeostatic parameters KW - Adult KW - CD4-Positive T-Lymphocytes KW - CD8-Positive T-Lymphocytes KW - Case-Control Studies KW - Disease Progression KW - Female KW - HIV Infections KW - Homeostasis KW - Humans KW - Male KW - Middle Aged TI - Class-modeling analysis reveals T-cell homeostasis disturbances involved in loss of immune control in elite controllers. TY - research article VL - 16 ER -