RT Journal Article T1 The Efficacy of Therapeutic Respiratory Muscle Training Interventions in People with Bronchiectasis: A Systematic Review and Meta-Analysis. A1 Martín-Valero, Rocio A1 Jimenez-Cebrian, Ana Maria A1 Moral-Munoz, Jose A A1 de-la-Casa-Almeida, Maria A1 Rodriguez-Huguet, Manuel A1 Casuso-Holgado, Maria Jesus K1 bronchiectasis K1 maximum expiratory pressure K1 maximum inspiratory pressure K1 meta-analysis K1 respiratory muscle strength K1 respiratory muscle training AB Background: Respiratory muscle dysfunction is an important health problem with high morbidity and mortality and associated costs in patients with bronchiectasis (BC). The aim of this study was to analyse the effects of therapeutic respiratory muscle training (RMT) interventions on improving sputum clearance, ventilator function, muscle strength and functional capacity in BC. Methods: Systematic review and meta-analysis were conducted following PRISMA guidelines. Two independent investigators searched using several electronic databases. The methodological quality of nine studies was assessed using the PEDro scale. Study selection/eligibility criteria: The following were included: randomised controlled trials, randomised crossover trials and pilot studies of patients with BC that used the intervention as RMT (inspiratory/expiratory) and evaluations of respiratory muscle strength (maximal expiratory pressure/maximal inspiratory pressure). This systematic review was registered in PROSPERO (CRD42017075101). Nine studies were included, five of which obtained an A recommendation grade, three with B, and one with C. Study quality was poor to good (mean PEDro Score of 6.375 out of 10). Studies had small sample sizes (8-98). Results show improvements on PImax in favour of therapeutic respiratory muscle training intervention (MD = 6.08; 95% CI = 1.38, 10.77; p SN 2077-0383 YR 2020 FD 2020-01-15 LK https://hdl.handle.net/10668/28352 UL https://hdl.handle.net/10668/28352 LA en DS RISalud RD Apr 17, 2025