TY - JOUR AU - Rada, Patricia AU - Mosquera, Alejandra AU - Muntané, Jordi AU - Ferrandiz, Francisco AU - Rodriguez-Mañas, Leocadio AU - de Pablo, Flora AU - González-Canudas, Jorge AU - Valverde, Ángela M PY - 2018 DO - 10.1016/j.fct.2018.11.019 UR - http://hdl.handle.net/10668/13167 T2 - Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association AB - The liver is a main target tissue of the biguanide metformin which activates AMP-activated protein kinase (AMPK). We previously reported that administration of metformin glycinate showed a greater decrease of glycated hemoglobin A1c than a placebo in... LA - en KW - Diabetes KW - Glucose homeostasis KW - Insulin resistance KW - Liver KW - Metformin KW - AMP-Activated Protein Kinases KW - Acetyl-CoA Carboxylase KW - Animals KW - Diabetes Mellitus, Type 2 KW - Female KW - Glucose KW - Glycated Hemoglobin KW - Hepatocytes KW - Humans KW - Insulin KW - Liver KW - Male KW - Metformin KW - Mice KW - Mice, Inbred C57BL KW - Mice, Obese KW - Phosphorylation TI - Differential effects of metformin glycinate and hydrochloride in glucose production, AMPK phosphorylation and insulin sensitivity in hepatocytes from non-diabetic and diabetic mice. TY - research article VL - 123 ER -