TY - JOUR AU - Urbanová, Kristína AU - Ramírez-Macías, Inmaculada AU - Martín-Escolano, Rubén AU - Rosales, María José AU - Cussó, Olaf AU - Serrano, Joan AU - Company, Anna AU - Sánchez-Moreno, Manuel AU - Costas, Miquel AU - Ribas, Xavi AU - Marín, Clotilde PY - 2018 DO - 10.3390/molecules24010134 UR - http://hdl.handle.net/10668/13370 T2 - Molecules (Basel, Switzerland) AB - The spectrum and efficacy of available antileishmanial drugs is limited. In the present work we evaluated in vitro the antiproliferative activity of 11 compounds based on tetradentate polyamines compounds against three Leishmania species (L.... LA - en KW - Leishmania spp. KW - SOD KW - amastigote KW - antileishmania KW - antiproliferative KW - promastigote KW - tetradentate polyaminic compounds KW - ultrastructure KW - Animals KW - Antiprotozoal Agents KW - Cell Line KW - Gene Expression Regulation, Enzymologic KW - Leishmania KW - Macrophages KW - Mice KW - Microscopy, Electron, Transmission KW - Molecular Structure KW - Parasitic Sensitivity Tests KW - Polyamines KW - Protozoan Proteins KW - Superoxide Dismutase TI - Effective Tetradentate Compound Complexes against Leishmania spp. that Act on Critical Enzymatic Pathways of These Parasites. TY - research article VL - 24 ER -