RT Journal Article
T1 Access to kidney transplantation in European adults aged 75-84 years and related outcomes: an analysis of the European Renal Association-European Dialysis and Transplant Association Registry.
A1 Pippias, Maria
A1 Stel, Vianda S
A1 Kramer, Anneke
A1 Abad Diez, Jose M
A1 Aresté-Fosalba, Nuria
A1 Ayav, Carole
A1 Buturovic, Jadranka
A1 Caskey, Fergus J
A1 Collart, Frederic
A1 Couchoud, Cécile
A1 De Meester, Johan
A1 Heaf, James G
A1 Helanterä, Ilkka
A1 Hemmelder, Marc H
A1 Kostopoulou, Myrto
A1 Noordzij, Marlies
A1 Pascual, Julio
A1 Palsson, Runolfur
A1 Reisaeter, Anna Varberg
A1 Traynor, Jamie P
A1 Massy, Ziad
A1 Jager, Kitty J
K1 Europe
K1 elderly
K1 epidemiology
K1 graft survival
K1 kidney transplantation
AB To what extent access to, and allocation of kidney transplants and survival outcomes in patients aged ≥75 years have changed over time in Europe is unclear. We included patients aged ≥75-84 years (termed older adults) receiving renal replacement therapy in thirteen European countries between 2005 and 2014. Country differences and time trends in access to, and allocation of kidney transplants were examined. Survival outcomes were determined by Cox regression analyses. Between 2005 and 2014, 1392 older adult patients received 1406 transplants. Access to kidney transplantation varied from ~0% (Slovenia, Greece and Denmark) to ~4% (Norway and various Spanish regions) of all older adult dialysis patients, and overall increased from 0.3% (2005) to 0.9% (2014). Allocation of kidney transplants to older adults overall increased from 0.8% (2005) to 3.2% (2014). Seven-year unadjusted patient and graft survival probabilities were 49.1% (95% confidence interval, 95% CI: 43.6; 54.4) and 41.7% (95% CI: 36.5; 46.8), respectively, with a temporal trend towards improved survival outcomes. In conclusion, in the European dialysis population aged ≥75-84 years access to kidney transplantation is low, and allocation of kidney transplants remains a rare event. Though both are increasing with time and vary considerably between countries. The trend towards improved survival outcomes is encouraging. This information can aid informed decision-making regarding treatment options.
YR 2018
FD 2018-03-02
LK http://hdl.handle.net/10668/12066
UL http://hdl.handle.net/10668/12066
LA en
DS RISalud
RD Apr 8, 2025