RT Journal Article
T1 Critical Care in SARS-CoV-2 Infected Pregnant Women: A Prospective Multicenter Study.
A1 Álvarez Bartolomé, Ana
A1 Abdallah Kassab, Nadia Akram
A1 Cruz Melguizo, Sara
A1 de la Cruz Conty, María Luisa
A1 Forcen Acebal, Laura
A1 Abascal Saiz, Alejandra
A1 Pintado Recarte, Pilar
A1 Martinez Varea, Alicia
A1 Cerrillos Gonzalez, Lucas
A1 García Fernández, Javier
A1 Martínez Pérez, Oscar
K1 coronavirus disease 2019 (COVID-19)
K1 intensive care
K1 pneumonia
K1 pregnancy
K1 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
AB Evidence suggests that pregnant women are at a higher risk of complications compared to the general population when infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the reasons that lead them to need intensive care are not clear. This is a prospective multicenter study of SARS-CoV-2 positive pregnant women, registered by the Spanish Obstetric Emergency Group, with the objective to define the characteristics of the mothers who were admitted to the Intensive Care Unit (ICU) and to investigate the causes and risk factors for ICU admission. A total of 1347 infected pregnant women were registered and analyzed, of whom, 35 (2.6%) were admitted to the ICU. No differences in maternal characteristics or comorbidities were observed between ICU and non-ICU patients, except for in vitro fertilization and multiple pregnancies. The main causes of admission to the ICU were non-obstetric causes (worsening of the maternal condition and respiratory failure due to SARS-CoV-2 pneumonia, 40%) and a combination of coronavirus disease 2019 (COVID-19) symptoms and obstetrical complications (31.4%). The multivariable logistic analysis confirmed a higher risk of ICU admission when pre-eclampsia or hemorrhagic events coexist with pneumonia. The incidence of thromboembolic events and disseminated intravascular coagulation were also significantly higher among patients admitted to the ICU. Therefore, surveillance and rapid intervention should be intensified in SARS-CoV-2 infected pregnant women with the mentioned risk factors and complications. Emphasis should always be placed on anticoagulant therapy in these patients due to the increased thromboembolic risk, C-section surgery and immobilization in the ICU.
SN 2227-9059
YR 2022
FD 2022-02-17
LK http://hdl.handle.net/10668/20820
UL http://hdl.handle.net/10668/20820
LA en
DS RISalud
RD Apr 9, 2025