RT Journal Article
T1 Sensitisation to Pollen Allergens in Children and Adolescents of Different Ancestry Born and Living in the Same Area.
A1 Somoza, Maria Luisa
A1 Pérez-Sánchez, Natalia
A1 Torres-Rojas, Isabel
A1 Martín-Pedraza, Laura
A1 Blanca-López, Natalia
A1 Victorio Puche, Laura
A1 Abel Fernández González, Eva
A1 López Sánchez, José Damián
A1 Fernández-Sánchez, Javier
A1 Fernández-Caldas, Enrique
A1 Villalba, Mayte
A1 Ruano, Francisco Javier
A1 Cornejo-García, José Antonio
A1 Canto, Gabriela
A1 Blanca, Miguel
K1 ancestry
K1 children/adolescents
K1 molecular components
K1 olive tree pollen
K1 pollen sensitisation
K1 respiratory allergy
AB Allergy can start at early ages, with genetic and environmental factors contributing to its development. The study aimed to describe the pattern of sensitisation and allergy in children and adolescents of Spanish versus Moroccan ancestry but born in the same rural area of Spain. Participants were children and adolescents (3-19 years) of Spanish or Moroccan descent, born in Blanca, Murcia (Spain). A detailed questionnaire was completed, and skin prick tests were performed to assess reactions to the most prevalent pollen allergens (O. europaea, P. pratense, S. kali, C. arizonica, P. acerifolia, A. vulgaris and P. judaica) plus molecular components Ole e 1 and Ole e 7. The association with ancestry was verified by studying participants' parents. The study included 693 participants: 48% were aged 3-9 years and 52%, 10-19 years; 80% were of Spanish descent and 20% of Moroccan descent. Sensitisation to Olea europaea, Phleum pratense, Salsola kali and Cupressus arizonica were slightly higher in the Spanish group. The only significant differences were observed in sensitisation to Ole e 1 (p=0.02). Rhinitis, conjunctivitis, and rhinitis plus asthma were significantly higher in the Spanish group (p=0.03, p=0.02, p=0.007, respectively). The sensitisation pattern differed between Spanish and Moroccan parents, and between Moroccan parents and their children, but not between Spanish parents and their children. Both environment and ancestry may influence sensitisation and symptoms. Although the environment seems to have a stronger influence, other factors may contribute to the differences in prevalence and in the clinical entities in people of Spanish versus Moroccan descent.
SN 1178-6965
YR 2022
FD 2022-09-26
LK http://hdl.handle.net/10668/20470
UL http://hdl.handle.net/10668/20470
LA en
DS RISalud
RD Apr 11, 2025