TY - JOUR AU - Pernas, Maria AU - Tarancon-Diez, Laura AU - Rodriguez-Gallego, Esther AU - Gomez, Josep AU - Prado, Julia G. AU - Casado, Concepcion AU - Dominguez-Molina, Beatriz AU - Olivares, Isabel AU - Coiras, Maite AU - Leon, Agathe AU - Rodriguez, Carmen AU - Benito, Jose Miguel AU - Rallon, Norma AU - Plana, Montserrat AU - Martinez-Madrid, Onofre AU - Dapena, Marta AU - Iribarren, Jose Antonio AU - del Romero, Jorge AU - Garcia, Felipe AU - Alcami, Jose AU - Munoz-Fernandez, MaAngeles AU - Vidal, Francisco AU - Leal, Manuel AU - Lopez-Galindez, Cecilio AU - Ruiz-Mateos, Ezequiel AU - ECRIS Integrated Spanish AIDS Res PY - 2018 DO - 10.1128/JVI.01805-17 SN - 0022-538X UR - http://hdl.handle.net/10668/19026 T2 - Journal of virology AB - HIV-1 elite controllers (EC) maintain undetectable viral loads (VL) in the absence of antiretroviral treatment. However, these subjects have heterogeneous clinical outcomes, including a proportion that loses HIV-1 control over time. In this work, we... LA - en PB - Amer soc microbiology KW - HIV-1 elite controllers KW - T-cell response KW - viral diversity KW - inflammatory biomarkers KW - HIV-1 controllers KW - inflammation KW - Immunodeficiency-virus type-1 KW - Cd8(+) t-cells KW - Viral load KW - Evolution KW - Suppression KW - Rantes KW - Rates KW - Nonprogressors KW - Heterogeneity KW - Polymorphism TI - Factors Leading to the Loss of Natural Elite Control of HIV-1 Infection TY - research article VL - 92 ER -