TY - JOUR AU - Taieb, Julien AU - Rivera, Fernando AU - Siena, Salvatore AU - Karthaus, Meinolf AU - Valladares-Ayerbes, Manuel AU - Gallego, Javier AU - Geissler, Michael AU - Koukakis, Reija AU - Demonty, Gaston AU - Peeters, Marc PY - 2017 DO - 10.1007/s00432-017-2534-z UR - http://hdl.handle.net/10668/11743 T2 - Journal of cancer research and clinical oncology AB - To report exploratory analyses of early tumour shrinkage (ETS) and depth of response (DpR) in patients with RAS wild-type (WT) metastatic colorectal cancer (mCRC), receiving the first-line treatment in three randomised panitumumab trials. Data from... LA - en KW - Depth of response KW - Early tumour shrinkage KW - Metastatic colorectal cancer KW - Panitumumab KW - Survival KW - Adult KW - Aged KW - Aged, 80 and over KW - Antibodies, Monoclonal KW - Antineoplastic Combined Chemotherapy Protocols KW - Colorectal Neoplasms KW - Female KW - Fluorouracil KW - GTP Phosphohydrolases KW - Humans KW - Leucovorin KW - Male KW - Membrane Proteins KW - Middle Aged KW - Organoplatinum Compounds KW - Panitumumab KW - Proto-Oncogene Proteins B-raf KW - Proto-Oncogene Proteins p21(ras) KW - Treatment Outcome KW - Young Adult TI - Exploratory analyses assessing the impact of early tumour shrinkage and depth of response on survival outcomes in patients with RAS wild-type metastatic colorectal cancer receiving treatment in three randomised panitumumab trials. TY - research article VL - 144 ER -