TY - JOUR AU - Garrido, Federico AU - Perea, Francisco AU - Bernal, Mónica AU - Sánchez-Palencia, Abel AU - Aptsiauri, Natalia AU - Ruiz-Cabello, Francisco PY - 2017 DO - 10.3390/vaccines5010007 UR - http://hdl.handle.net/10668/2691 T2 - Vaccines AB - Tumor immune escape is associated with the loss of tumor HLA class I (HLA-I) expression commonly found in malignant cells. Accumulating evidence suggests that the efficacy of immunotherapy depends on the expression levels of HLA class I molecules on... LA - en PB - MDPI KW - HLA class I loss KW - Tumor infiltrating lymphocytes (TILs) KW - Tumor immune escape KW - Humanos KW - Inmunoterapia KW - Activación de linfocitos KW - Macrófagos KW - Mutación KW - Neoplasia KW - Linfocitos t citotóxicos KW - Escape del Tumor KW - Microambiente tumoral KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Biological Therapy::Immunomodulation::Immunotherapy KW - Medical Subject Headings::Phenomena and Processes::Immune System Phenomena::Immune System Processes::Lymphocyte Activation KW - Medical Subject Headings::Anatomy::Cells::Phagocytes::Macrophages KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Variation::Mutation KW - Medical Subject Headings::Diseases::Neoplasms KW - Medical Subject Headings::Anatomy::Cells::Blood Cells::Leukocytes::Leukocytes, Mononuclear::Lymphocytes::Lymphocyte Subsets::T-Lymphocyte Subsets::T-Lymphocytes, Cytotoxic KW - Medical Subject Headings::Phenomena and Processes::Immune System Phenomena::Immune System Processes::Tumor Escape KW - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cellular Microenvironment::Tumor Microenvironment TI - The Escape of Cancer from T Cell-Mediated Immune Surveillance: HLA Class I Loss and Tumor Tissue Architecture TY - research article ER -