RT Journal Article
T1 Epidemiologic changes in bloodstream infections in Andalucía (Spain) during the last decade.
A1 Martinez-Perez-Crespo, P M
A1 Lopez-Cortes, L E
A1 Retamar-Gentil, P
A1 Lanz-Garcia, J F
A1 Vinuesa-Garcia, D
A1 Leon, E
A1 Sanchez-Calvo, J M
A1 Galan-Sanchez, F
A1 Natera-Kindelan, C
A1 Del-Arco-Jimenez, A
A1 Sanchez-Porto, A
A1 Herrero-Rodriguez, C
A1 Becerril-Carral, B
A1 Reche-Molina, I M
A1 Reguera-Iglesias, J M
A1 Perez-Camacho, I
A1 Guzman-Garcia, M
A1 Lopez-Hernandez, I
A1 Rodriguez-Baño, J
K1 Aetiology
K1 Bacteraemia
K1 Bloodstream infection
K1 Epidemiology
K1 Incidence
K1 AGS - Campo de Gibraltar Oeste
K1 AGS - Jerez, Costa Noroeste y Sierra de Cáidz
K1 AGS - Campo de Gibraltar Este
K1 AGS - Norte de Jaén
K1 AGS - Sur de Sevilla
AB During the last decade, some changes in the epidemiology of invasive infections have been reported; however, specific studies with patient-level data are scarce. The aim of this study was to describe and evaluate the epidemiologic changes in bloodstream infections (BSI) during the last decade in Andalucía, Spain. Data from two prospective cohorts of BSI in adults with the same methodology performed 10 years apart in 11 hospitals (eight tertiary and three community) in Andalucía, Spain, were compared; the 2006-7 cohort study was performed between October 2006 and March 2007, and the 2016-17 cohort study was performed between October 2016 and March 2017. Population-based incidence rates were calculated and extrapolated for 1 year. Relative risk ratios were calculated between the 2 periods. Multivariate analyses were performed by logistic regression. Overall, 1262 episodes of BSI were included, 563 (44.6%) in 2006-7 and 699 (55.3%) in 2016-17. Multivariate models selected the following changes in patients' features in 2016-17, after controlling for type of acquisition: higher age (odds ratio (OR) = 1.02; 95% confidence interval [CI] 1.01-1.03), lower urinary catheter (OR = 0.37; 95% CI, 0.26-0.48) and lower Pitt score (OR = 0.76; 95% CI, 0.71-0.82). Adjusted estimations considering patients' features and exposure to procedures showed a reduction in coagulase-negative staphylococci (OR = 0.47; 95% CI, 0.32-0.69), and an increase in Proteus spp. (OR = 3.12; 95% CI, 1.18-8.23) and Candida spp. (OR = 3.01; 95% CI, 1.03-8.86). We found relevant epidemiologic changes in BSI in our area, including rates, frequency of acquisition types, changes in patient's profiles and aetiologic agents.
PB Elsevier
YR 2020
FD 2020-05-26
LK http://hdl.handle.net/10668/15658
UL http://hdl.handle.net/10668/15658
LA en
NO Martínez Pérez-Crespo PM, López-Cortés LE, Retamar-Gentil P, García JFL, Vinuesa García D, León E, et al. Epidemiologic changes in bloodstream infections in Andalucía (Spain) during the last decade. Clin Microbiol Infect. 2021 Feb;27(2):283.e9-283.e16
NO This work was financed by grants from Plan Nacional de IþDþi 2013-2016, Instituto de Salud Carlos III, Subdireccion General de Redes y Centros de Investigacion Cooperativa, Ministerio de Ciencia, Innovacion y Universidades (PI16/01432); Spanish Network for Research in Infectious Diseases (REIPI) (RD16/0016/0001; RD16/ 0016/0008); and cofinanced by European Development Regional Fund ‘A way to achieve Europe,’ Operative Program Intelligent Growth 2014e2020. JRB and PR participated in accredited educational activities funded my Merck though unrestricted grants. LELC hasservedasscientific advisor for Novartis, speaker for MSD, Pfizer, Angelini and ViiV and trainer for MSD and ViiV. FGS has served as speaker for PfizerandAstellas. Theotherauthorsreportnoconflicts of interest relevant to this article.
DS RISalud
RD Apr 7, 2025