TY - JOUR AU - Vítor, Alexandra C. AU - Huertas, Pablo AU - Legube, Gaëlle AU - de Almeida, Sérgio F. PY - 2020 DO - 10.3389/fmolb.2020.00024 UR - http://hdl.handle.net/10668/3734 T2 - Frontiers in Molecular Biosciences AB - To ward off against the catastrophic consequences of persistent DNA double-strand breaks (DSBs), eukaryotic cells have developed a set of complex signaling networks that detect these DNA lesions, orchestrate cell cycle checkpoints and ultimately lead... LA - en PB - Frontiers KW - DNA repair KW - Homologous recombination (HR) KW - Non-homologous DNA end joining KW - Chromatin KW - DNA damage KW - Reparación del ADN KW - Recombinación homóloga KW - Reparación del ADN por unión de extremidades KW - Cromatina KW - Daño del ADN KW - Roturas del ADN de doble cadena KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Processes::DNA Damage::DNA Breaks::DNA Breaks, Double-Stranded KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Processes::DNA Repair KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Processes::Recombination, Genetic::Homologous Recombination KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Processes::DNA Repair::DNA End-Joining Repair KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Structures::Chromosome Structures::Chromatin KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Processes::DNA Damage KW - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Cycle::Cell Cycle Checkpoints KW - Medical Subject Headings::Chemicals and Drugs::Nucleic Acids, Nucleotides, and Nucleosides::Nucleic Acids::DNA KW - Medical Subject Headings::Disciplines and Occupations::Natural Science Disciplines::Biological Science Disciplines::Biology::Genetics::Genomics TI - Studying DNA Double-Strand Break Repair: An Ever-Growing Toolbox TY - review article ER -