RT Journal Article
T1 Oral and general health-related quality of life in patients treated for oral cancer compared to control group.
A1 Barrios, Rocío
A1 Bravo, Manuel
A1 Gil-Montoya, Jose Antonio
A1 Martínez-Lara, Ildefonso
A1 García-Medina, Blas
A1 Tsakos, Georgios
K1 Oral cancer
K1 Quality of life
K1 SF-12
K1 OHIP
K1 OIDP
K1 Neoplasias de la Boca
K1 Calidad de vida
K1 Cuestionarios
K1 Grupos control
K1 Humanos
K1 Masculino
K1 Salud bucal
K1 Neoplasias orofaríngeas
K1 Evaluación del desenlace (asistencia sanitaria)
K1 Clase social
AB BACKGROUNDHealth-related quality of life (HRQoL) is gaining importance as a valuable outcome measure in oral cancer area. The aim of this study was to assess the general and oral HRQoL of oral and oropharyngeal cancer patients 6 or more months after treatment and compare them with a population free from this disease.METHODSA cross-sectional study was carried out with patients treated for oral cancer at least 6 months post-treatment and a gender and age group matched control group. HRQoL was measured with the 12-Item Short Form Health Survey (SF-12); oral HRQoL (OHRQoL) was evaluated using the Oral Health Impact Profile (OHIP-14) and the Oral Impacts on Daily Performances (OIDP). Multivariable regression models assessed the association between the outcomes (SF-12, OHIP-14 and OIDP) and the exposure (patients versus controls), adjusting for sex, age, social class, functional tooth units and presence of illness.RESULTSFor patients (n = 142) and controls (n = 142), 64.1% were males. The mean age was 65.2 (standard deviation (sd): 12.9) years in patients and 67.5 (sd: 13.7) years in controls. Patients had worse SF-12 Physical Component Summary scores than controls even in fully the adjusted model [β-coefficient = -0.11 (95% CI: -5.12-(-0.16)]. The differences in SF-12 Mental Component Summary were not statistically significant. Regarding OHRQoL patients had 11.63 (95% CI: 6.77-20.01) higher odds for the OHIP-14 and 21.26 (95% CI: 11.54-39.13) higher odds for OIDP of being in a worse category of OHRQoL compared to controls in the fully adjusted model.CONCLUSIONAt least 6 months after treatment, oral cancer patients had worse OHRQoL, worse physical HRQoL and similar psychological HRQoL than the general population.
PB BioMed Central
YR 2015
FD 2015-01-23
LK http://hdl.handle.net/10668/2115
UL http://hdl.handle.net/10668/2115
LA en
NO Barrios R, Bravo M, Gil-Montoya JA, Martínez-Lara I, García-Medina B, Tsakos G. Oral and general health-related quality of life in patients treated for oral cancer compared to control group. Health Qual Life Outcomes. 2015; 13:9
NO Journal Article; Research Support, Non-U.S. Gov't;
DS RISalud
RD Mar 5, 2025