TY  - JOUR
AU  - Perez-Ruixo, Carlos
AU  - Ackaert, Oliver
AU  - Ouellet, Daniele
AU  - Chien, Caly
AU  - Uemura, Hiroji
AU  - Olmos, David
AU  - Mainwaring, Paul
AU  - Lee, Ji Youl
AU  - Yu, Margaret K
AU  - Perez-Ruixo, Juan Jose
AU  - Smith, Matthew R
AU  - Small, Eric J
PY  - 2020
DO  - 10.1158/1078-0432.CCR-20-1041
UR  - http://hdl.handle.net/10668/15781
T2  - Clinical cancer research : an official journal of the American Association for Cancer Research
AB  - To evaluate the relationship between exposure of apalutamide and its active metabolite, N-desmethyl-apalutamide, and selected clinical efficacy and safety parameters in men with high-risk nonmetastatic castration-resistant prostate cancer. An...
LA  - en
KW  - Adult
KW  - Androgen Receptor Antagonists
KW  - Area Under Curve
KW  - Dose-Response Relationship, Drug
KW  - Drug Eruptions
KW  - Humans
KW  - Male
KW  - Middle Aged
KW  - Progression-Free Survival
KW  - Prostatic Neoplasms, Castration-Resistant
KW  - Thiohydantoins
KW  - Weight Loss
TI  - Efficacy and Safety Exposure-Response Relationships of Apalutamide in Patients with Nonmetastatic Castration-Resistant Prostate Cancer.
TY  - research article
VL  - 26
ER  -