TY  - JOUR
AU  - García-Cuesta, Eva M
AU  - Rodríguez-Frade, José Miguel
AU  - Gardeta, Sofía R
AU  - D'Agostino, Gianluca
AU  - Martínez, Pablo
AU  - Soler Palacios, Blanca
AU  - Cascio, Graciela
AU  - Wolf, Tobias
AU  - Mateos, Nicolas
AU  - Ayala-Bueno, Rosa
AU  - Santiago, César A
AU  - Lucas, Pilar
AU  - Llorente, Lucia
AU  - Allende, Luis M
AU  - González-Granado, Luis Ignacio
AU  - Martín-Cófreces, Noa
AU  - Roda-Navarro, Pedro
AU  - Sallusto, Federica
AU  - Sánchez-Madrid, Francisco
AU  - García-Parajo, María F
AU  - Martínez-Muñoz, Laura
AU  - Mellado, Mario
PY  - 2022
DO  - 10.1073/pnas.2119483119
UR  - http://hdl.handle.net/10668/19666
T2  - Proceedings of the National Academy of Sciences of the United States of America
AB  - Chemokine receptor nanoscale organization at the cell membrane is orchestrated by the actin cytoskeleton and influences cell responses. Using single-particle tracking analysis we show that CXCR4R334X, a truncated mutant chemokine receptor linked to...
LA  - en
KW  - WHIM syndrome
KW  - cell migration
KW  - chemokine receptors
KW  - Actin Depolymerizing Factors
KW  - Cell Membrane
KW  - Cell Movement
KW  - Humans
KW  - Mutation
KW  - Primary Immunodeficiency Diseases
KW  - Receptors, CXCR4
KW  - Single Molecule Imaging
KW  - Warts
TI  - Altered CXCR4 dynamics at the cell membrane impairs directed cell migration in WHIM syndrome patients.
TY  - research article
VL  - 119
ER  -