RT Journal Article
T1 Infectious processes and systemic lupus erythematosus.
A1 Illescas-Montes, Rebeca
A1 Corona-Castro, Claudia Cristina
A1 Melguizo-Rodriguez, Lucia
A1 Ruiz, Concepcion
A1 Costela-Ruiz, Víctor J
K1 bacteria
K1 etiology
K1 infection
K1 systemic lupus erythematosus
K1 virus
AB Systemic lupus erythematosus (SLE) is an autoimmune chronic inflammatory disease of unknown etiology, although genetic and environmental factors appear to contribute to its pathogenesis. Specifically, infectious processes are associated with SLE onset and exacerbation. However, we are far from a complete understanding of the interactions between infectious agents and the host, explaining the interest in gathering updated scientific information on this topic. According to the literature, the pathogens most frequently associated with SLE are viruses, notably human endogenous retroviruses, Epstein-Barr virus, parvovirus B19, cytomegalovirus and human immunodeficiency virus type 1, alongside certain bacterial components that can also trigger activation of the immune system. The mechanisms underlying autoreactivity remain unclear but various explanations have been proposed, including immunological changes responsible for infectious processes or molecular mimicry between host structures and those of infectious agents.
PB Wiley-Blackwell Publishing Ltd.
YR 2019
FD 2019-07-25
LK http://hdl.handle.net/10668/14366
UL http://hdl.handle.net/10668/14366
LA en
NO Illescas-Montes R, Corona-Castro CC, Melguizo-Rodríguez L, Ruiz C, Costela-Ruiz VJ. Infectious processes and systemic lupus erythematosus. Immunology. 2019 Nov;158(3):153-160.
DS RISalud
RD Apr 11, 2025