RT Journal Article
T1 Nalidixic acid surrogate test for susceptibility to ciprofloxacin in Salmonella. Revisiting the question.
A1 Guzmán-Martín, José Luis
A1 Navarro-Marí, José María
A1 Expósito-Ruiz, Manuela
A1 Gutiérrez-Fernández, José
K1 Salmonella
K1 ciprofloxacin
K1 enteritis
K1 nalidixic acid
K1 stools
AB We investigated the reliability of nalidixic acid (NA) susceptibility as a marker of ciprofloxacin susceptibility in Salmonella, analysing 302 stool isolates. NC53 of the MicroScan system was used for NA susceptibility tests and the E-test was used for ciprofloxacin susceptibility tests. Among the isolates, 178 (58.9 %) were serogroup B, 74 (24.5 %) were serogroup D, 27 (8.9 %) were serogroup C and 23 (7.6 %) were from other minor serogroups. Globally, susceptibility to NA correctly predicted the susceptibility of Salmonella to ciprofloxacin, with a sensitivity of 81.5 %, a specificity of 97.6 %, and positive and negative predictive values of 88 and 96 %, respectively. However, there were differences among the serogroups in terms of sensitivity (P
YR 2018
FD 2018
LK http://hdl.handle.net/10668/12474
UL http://hdl.handle.net/10668/12474
LA en
DS RISalud
RD Apr 12, 2025