RT Journal Article
T1 Is routine ophthalmoscopy really necessary in candidemic patients?
A1 Vena, Antonio
A1 Muñoz, Patricia
A1 Padilla, Belen
A1 Valerio, Maricela
A1 Sanchez, Maria Isabel
A1 Puig-Asensio, Mireia
A1 Fortun, Jesus
A1 Fernandez-Ruiz, Mario
A1 Merino, Paloma
A1 Losa, Juan Emilio
A1 Loza, Ana
A1 Rivas, Rosa Ana
A1 Bouza, Emilio
A1 CANDIPOP Project, GEIH-GEMICOMED (SEIMC), and REIPI
AB The purpose of this study was to determine among patients with candidemia the real rate of ophthalmoscopy and the impact of performing ocular assessment on the outcome of the disease. We performed a post hoc analysis of a prospective, multicenter, population-based candidemia surveillance program implemented in Spain during 2010-2011 (CANDIPOP). Ophthalmoscopy was performed in only 168 of the 365 patients with candidemia (46%). Ocular lesions related to candidemia were found in only 13/168 patients (7.7%), of whom 1 reported ocular symptoms (incidence of symptomatic disease in the whole population, 0.27% [1/365]). Ophthalmological findings led to a change in antifungal therapy in only 5.9% of cases (10/168), and performance of the test was not related to a better outcome. Ocular candidiasis was not associated with a worse outcome and progressed favorably in all but 1 evaluable patient, who did not experience vision loss. The low frequency of ophthalmoscopy and ocular involvement and the asymptomatic nature of ocular candidiasis, with a favorable outcome in almost all cases, lead us to reconsider the need for systematic ophthalmoscopy in all candidemic patients.
YR 2017
FD 2017-10-24
LK http://hdl.handle.net/10668/11721
UL http://hdl.handle.net/10668/11721
LA en
DS RISalud
RD Apr 17, 2025