RT Generic
T1 Treatment of Dysphagia Oculopharyngeal muscular dystrophy. Systematic review
A1 Isabel Sanz-Sanchez, Cristina
A1 Emilio Cazorla-Ramos, Oscar
A1 Valle-Olsen, Sofia
A1 Verge-Gonzalez, Jesus
A1 Antonio Perez-Arcos, Jose
K1 Oculopharyngeal muscular dystrophy
K1 dysphagia
K1 treatment
K1 upper esophageal sphincter myotomy
K1 systematic review
K1 Botulinum toxin
K1 Cricopharyngeal myotomy
K1 Dilatation
K1 Dysfunction
K1 Diagnosis
K1 Safety
AB Introduction and objective: Dysphagia has been reported to be a concern in adults with oculopharyngeal muscular dystrophy (OPMD). This problem can result in several complications including aspiration pneumonia, reduced quality of life and an increase in mortality rate. The objective was to evaluation and comparison of the different current treatments available. Method: We performed a systematic review in the databases PubMed, EMBASE, Cochrane Library and Scielo published in the period 1990-2020, selecting those articles in wich the dysphagia in OPMD is treated. Results: We include 9 articles with a total of 164 with this disease, in which surgical myotomy of the upper esophageal sphincter was the most frequently performed procedure in 6 series with 117 patients, followed by endoscopic dilatation and botulinum toxin. The improvement in the 9 series is around 77, 3% and if we consider surgical myotomies is 84, 66%. The incidence of complications is low, we do not find associated mortality in any of the series. Discussion and conclusions: The priority of patient's treatment is determining the degree and severity of the dysphagia that is the main factor determining prognosis. Upper esophageal sphincter myotomy is the most effective and widely used of all the possibilities, with high rate of success and low rate of complications.
PB Univ salamanca, ediciones
YR 2021
FD 2021-01-01
LK https://hdl.handle.net/10668/26914
UL https://hdl.handle.net/10668/26914
LA es
DS RISalud
RD Apr 17, 2025