TY - JOUR AU - Gonzalez-Morena, Juan M AU - Sanchez-Gomez, Francisco J AU - Vida, Yolanda AU - Perez-Inestrosa, Ezequiel AU - Salas, Maria AU - Montañez, Maria I AU - Altomare, Alessandra AU - Aldini, Giancarlo AU - Pajares, Maria A AU - Perez-Sala, Dolores PY - 2022 DO - 10.3389/fphar.2021.807742 SN - 1663-9812 UR - http://hdl.handle.net/10668/20700 T2 - Frontiers in pharmacology AB - Allergic reactions to antibiotics are a major concern in the clinic. ß-lactam antibiotics are the class most frequently reported to cause hypersensitivity reactions. One of the mechanisms involved in this outcome is the modification of proteins by... LA - en PB - Frontiers Research Foundation KW - Acetylation KW - Allergic responses to drugs KW - Beta-lactam antibiotics KW - Mass spectrometry KW - Posttranslational modification KW - Protein modification by drugs KW - Anti-Bacterial Agents KW - Amoxicillin KW - Lysine KW - Molecular Docking Simulation KW - Phosphopyruvate Hydratase KW - Acetylation KW - Hypersensitivity TI - Amoxicillin Haptenation of α-Enolase is Modulated by Active Site Occupancy and Acetylation. TY - research article VL - 12 ER -