TY  - JOUR
AU  - Concha, Emilio G. de la
AU  - Cavanillas, María L.
AU  - Cénit, M. Carmen
AU  - Urcelay, Elena
AU  - Arroyo, Rafael
AU  - Fernández, Óscar
AU  - Álvarez-Cermeño, José C.
AU  - Leyva, Laura
AU  - Villar, Luisa M.
AU  - Núñez, Concepción
PY  - 2012
DO  - 10.1371/journal.pone.0031018
UR  - http://hdl.handle.net/10668/913
T2  - PloS One
AB  - BACKGROUNDMultiple sclerosis (MS) is a multifactorial disease with a genetic basis. The strongest associations with the disease lie in the Human Leukocyte Antigen (HLA) region. However, except for the DRB1*15:01 allele, the main risk factor associated...
LA  - en
PB  - Public Library of Science
KW  - HLA-DRB1*03:01 antigen
KW  - Antigeno HLA-DRB1*03:01
KW  - Estudios caso-control
KW  - Estudios de asociación genética
KW  - Predisposición genética a la enfermedad
KW  - Cadenas HLA-DRB1
KW  - Haplotipos
KW  - Humanos
KW  - Inmunoglobulina M
KW  - Esclerosis Múltiple
KW  - Factores de Riesgo
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Case-Control Studies
KW  - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genotype::Genetic Predisposition to Disease
KW  - Medical Subject Headings::Chemicals and Drugs::Biological Factors::Antigens::Isoantigens::Histocompatibility Antigens::HLA Antigens::HLA-D Antigens::HLA-DR Antigens::HLA-DR beta-Chains::HLA-DRB1 Chains
KW  - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genotype::Haplotypes
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Globulins::Serum Globulins::Immunoglobulins::Antibodies::Immunoglobulin Isotypes::Immunoglobulin M
KW  - Medical Subject Headings::Diseases::Nervous System Diseases::Demyelinating Diseases::Demyelinating Autoimmune Diseases, CNS::Multiple Sclerosis
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Probability::Risk::Risk Factors
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Genetic Techniques::Genetic Association Studies
TI  - DRB1*03:01 haplotypes: differential contribution to multiple sclerosis risk and specific association with the presence of intrathecal IgM bands.
TY  - research article
ER  -