RT Journal Article
T1 Clinical characteristics, health care resource utilization and direct medical costs of Rotavirus hospitalizations in Spain (2013-2018).
A1 Aristegui, Javier
A1 Alfayate-Miguelez, Santiago
A1 Carazo-Gallego, Begoña
A1 Garrote, Elisa
A1 Diaz-Munilla, Laura
A1 Mendizabal, Mikel
A1 Mendez-Hernandez, Maria
A1 Domenech, Elia
A1 Ferrer-Lorente, Belen
A1 Unsain-Mancisidor, Maria
A1 Ramos-Amador, Jose Tomas
A1 Illan-Ramos, Marta
A1 Croche-Santander, Borja
A1 Centeno-Malfaz, Fernando
A1 Rodriguez-Suarez, Julian
A1 Cotarelo-Suarez, Manuel
A1 San-Martin, Maria
A1 Ruiz-Contreras, Jesus
K1 Rotavirus
K1 Spain
K1 Acute gastroenteritis
K1 Direct costs
K1 Health care resources
K1 Hospitalization
AB Rotavirus (RV) is the most common cause of severe gastroenteritis (GE) in infants and young children worldwide and is associated with a significant clinical and economic burden. The objective of this study was to analyze the characteristics, healthcare resource utilization and the direct medical costs related to RVGE hospitalizations in Spain. An observational, multicenter, cross-sectional study was conducted from June 2013 to May 2018 at the pediatric departments of 12 hospitals from different Spanish regions. Children under 5 years of age admitted to the hospital with a confirmed diagnosis of RVGE were selected. Data on clinical characteristics, healthcare resource use and costs were collected from patient records and hospital databases. Most children hospitalized for RVGE did not have any previous medical condition or chronic disease. Forty-seven percent had previously visited the Emergency Room (ER), 27% had visited a primary care pediatrician, and 15% had received pharmacological treatment prior to hospital admission due to an RVGE episode. The average length of a hospital stay for RVGE was 5.6 days, and the mean medical costs of RVGE hospitalizations per episode ranged from 3,940€ to 4,100€. The highest direct medical cost was due to the hospital stay. This study showed a high burden of health resource utilization and costs related to the management of cases of RVGE requiring hospitalization. RV vaccination with high coverage rates should be considered to minimize the clinical and economic impacts of this disease on the health-care system.
PB Taylor & Francis
YR 2022
FD 2022-02-23
LK http://hdl.handle.net/10668/19695
UL http://hdl.handle.net/10668/19695
LA en
NO Arístegui J, Alfayate-Miguelez S, Carazo-Gallego B, Garrote E, Díaz-Munilla L, Mendizabal M, et al. Clinical characteristics, health care resource utilization and direct medical costs of Rotavirus hospitalizations in Spain (2013-2018). Hum Vaccin Immunother. 2022 Nov 30;18(5):2046961.
DS RISalud
RD Apr 8, 2025