TY - JOUR AU - Cebrián-Sastre, Esmeralda AU - Martín-Blecua, Isabel AU - Gullón, Sonia AU - Blázquez, Jesús AU - Castañeda-García, Alfredo PY - 2021 DO - 10.3390/cells10061314 UR - http://hdl.handle.net/10668/4426 T2 - Cells AB - The DNA repair endonuclease EndoMS/NucS is highly conserved in Archaea and Actinobacteria. This enzyme is able to recognize and cleave dsDNA carrying a mismatched base pair, and its activity is enhanced by the interaction with the sliding clamp of the... LA - en PB - MDPI KW - EndoMS/NucS KW - Non-canonical mismatch repair KW - Genome stability KW - Hypermutation KW - Antibiotic resistance KW - Actinobacteria KW - Mycobacterium tuberculosis KW - Reparación de la incompatibilidad de ADN KW - Inestabilidad genómica KW - Farmacorresistencia microbiana KW - Actinobacteria KW - ADN KW - Mutación KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Bacterial Proteins KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Variation::Mutation::Base Pair Mismatch KW - Medical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Genomic Instability KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Variation::Mutation::Mutation Rate KW - Medical Subject Headings::Organisms::Bacteria::Gram-Positive Bacteria::Actinobacteria KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Processes::DNA Repair::DNA Mismatch Repair KW - Medical Subject Headings::Phenomena and Processes::Microbiological Phenomena::Drug Resistance, Microbial KW - Medical Subject Headings::Organisms::Bacteria::Gram-Positive Bacteria::Actinobacteria::Actinomycetales::Mycobacteriaceae::Mycobacterium::Mycobacterium tuberculosis KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Phenotype TI - Control of Genome Stability by EndoMS/NucS-Mediated Non-Canonical Mismatch Repair TY - review article ER -