RT Journal Article T1 Activity-Oriented Antiedema Proprioceptive Therapy (TAPA) for Shoulder Mobility Improvement in Women with Upper Limb Lymphedema Secondary to Breast Cancer: A Multicenter Controlled Clinical Trial. A1 Muñoz-Alcaraz, Maria Nieves A1 Jimenez-Vilchez, Antonio Jose A1 Santamaria-Pelaez, Mirian A1 Perula-de Torres, Luis A A1 Olmo-Carmona, Maria Victoria A1 Muñoz-Garcia, Maria Teresa A1 Jorge-Gutierrez, Presentacion A1 Serrano-Merino, Jesus A1 Romero-Rodriguez, Esperanza A1 Rodriguez-Elena, Lorena A1 Refusta-Ainaga, Raquel A1 Lahoz-Sanchez, Maria Pilar A1 Miro-Palacios, Belen A1 Medrano-Cid, Mayra A1 Magallon-Botaya, Rosa A1 Minguez-Minguez, Luis A A1 Gonzalez-Santos, Josefa A1 Gonzalez-Bernal, Jeronimo J K1 Activity-oriented anti-edema therapy K1 Breast cancer K1 Complex decongestive therapy K1 Manual lymphatic drainage K1 Multidisciplinary oncological rehabilitation K1 Occupational therapy K1 Secondary lymphedema K1 Upper limb K1 Área Sanitaria Norte de Córdoba AB Lymphedema, secondary to breast cancer (BCRL), is the abnormal accumulation of protein-rich fluid in the interstitium caused by a malfunction of the lymphatic system. It causes swelling, deficiencies in upper limb functions and structures, sensory pain and emotional alterations, which have a chronic course and affect the upper limb's functionality. This study aims to verify the efficacy and efficiency in the upper limb´s functionality of a protocolized experimental approach based on occupational therapy, TAPA (activity-oriented proprioceptive antiedema therapy), in the rehabilitation of BCRL in stages I and II, comparing it with the conservative treatment considered as the standard, complex decongestive therapy (CDT), through a multicenter randomized clinical trial. a randomized and prospective clinical trial was conducted with experimental and control groups. Women diagnosed with BCRL belonging to institutions in Córdoba and Aragon (Spain) participated. Sociodemographic variables and those related to the functionality of the affected upper limb were evaluated before and after the intervention. The results showed statistically significant differences in the analysis of covariance performed for the variable joint balance of the shoulder´s external rotation (p = 0.045) that could be attributed to the intervention performed; however, the effect size was minimal (η2 ≤ 0.080). In the rest of the variables, no significant differences were found. TAPA may be an alternative to the conservative treatment of women with BCRL. It was shown to be just as effective for volume reduction and activity performance as CDT but more effective in improving external rotation in shoulder joint balance. PB MDPI SN 2077-0383 YR 2022 FD 2022-04-12 LK http://hdl.handle.net/10668/21272 UL http://hdl.handle.net/10668/21272 LA en NO Muñoz-Alcaraz MN, Jiménez-Vílchez AJ, Santamaría-Peláez M, Pérula-de Torres LA, Olmo-Carmona MV, Muñoz-García MT, et al. Activity-Oriented Antiedema Proprioceptive Therapy (TAPA) for Shoulder Mobility Improvement in Women with Upper Limb Lymphedema Secondary to Breast Cancer: A Multicenter Controlled Clinical Trial. J Clin Med. 2022 Apr 16;11(8):2234 DS RISalud RD Apr 8, 2025