TY - JOUR AU - García-Vilas, Javier A AU - Quesada, Ana R AU - Medina, Miguel Ángel PY - 2016 DO - 10.1016/j.foodchem.2016.10.111 UR - http://hdl.handle.net/10668/10683 T2 - Food chemistry AB - The health benefits of olive oil are attributed to their bioactive compounds, such as hydroxytyrosol. Previously, we demonstrated that hydroxytyrosol inhibits angiogenesis in vitro. The present study aimed to: i) get further insight into the effects... LA - en KW - Angiogenesis KW - Aortic ring assay KW - Bovine aorta endothelial cells (BAEC) KW - Chorioallantoic membrane (CAM) assay KW - Hydroxytyrosol KW - Matrix metalloproteinase (MMP) KW - Tissue inhibitor of metalloproteinase (TIMP) KW - Urokinase-type plasminogen activator (uPA) KW - Animals KW - Cattle KW - Endothelial Cells KW - Extracellular Matrix KW - Neovascularization, Physiologic KW - Phenylethyl Alcohol KW - Proteolysis TI - Hydroxytyrosol targets extracellular matrix remodeling by endothelial cells and inhibits both ex vivo and in vivo angiogenesis. TY - research article VL - 221 ER -