RT Conference Proceedings T1 Differences in early-onset vs. late-onset psoriatic arthritis: data from the respondia and regisponser studies. A1 Puche-Larrubla, M. A. A1 Ladehesa-Pineda, M. L. A1 Lopez-Montilla, M. D. A1 Collantes-Estevez, E. A1 Lopez-Medina, C. K1 Arthritis, Psoriatic K1 Age of Onset K1 Rheumatology K1 Statistics, Nonparametric K1 Spondylarthritis AB Background The prevalence of late-onset psoriatic arthritis (PsA) is increasing in parallel with the progressive aging of the population. The elderly population presents a greater functional deterioration and a greater number of comorbidities than the young people. With this study we aim to find clinically relevant differences to predict the evolution and prognosis of the disease depending on the onset of the symptoms to carry out a more exhaustive follow-up. Objectives To evaluate the association of the age at onset of PsA symptoms with the characteristics and burden of the disease. Methods Observational study that includes a subgroup of 231 patients with Psoriatic Arthritis (PsA) from the REGISPONSER study (Registry of Spondyloarthritis of Spanish Rheumatology) and the RESPONDIA study (Ibero-American Registry of Spondyloarthropathies). Patients with less than 10 years of disease duration (since the first symptom) were selected so that the sample was homogeneous. Patients were divided into two groups according to the age of PsA onset (early-onset: ≤40 years old and late-onset: ≥60 years old). The characteristics and burden of the disease were compared using the Student’s t-test/Mann-Whitney U test for quantitative variables or using the chi-square/Fisher test for qualitative variables. PB Bmj publishing group SN 0003-4967 YR 2022 FD 2022-05-23 LK http://hdl.handle.net/10668/20099 UL http://hdl.handle.net/10668/20099 LA en NO Puche Larrubia MÁ, Ladehesa Pineda ML, López Montilla MD, et al AB0828 Differences in early-onset vs. late-onset psoriatic arthritis: data from the RESPONDIA and REGISPONSER studies.Annals of the Rheumatic Diseases 2022;81:1540-1541 DS RISalud RD Sep 14, 2025