TY - JOUR AU - Felip, Enriqueta AU - Hirsh, Vera AU - Popat, Sanjay AU - Cobo, Manuel AU - Fülöp, Andrea AU - Dayen, Charles AU - Trigo, José M AU - Gregg, Richard AU - Waller, Cornelius F AU - Soria, Jean-Charles AU - Goss, Glenwood D AU - Gordon, James AU - Wang, Bushi AU - Palmer, Michael AU - Ehrnrooth, Eva AU - Gadgeel, Shirish M PY - 2017 DO - 10.1016/j.cllc.2017.06.002 UR - http://hdl.handle.net/10668/11425 T2 - Clinical lung cancer AB - In the phase III LUX-Lung 8 trial, afatinib significantly improved progression-free survival (PFS) and overall survival (OS) versus erlotinib in patients with squamous cell carcinoma (SCC) of the lung progressing during or after platinum-based... LA - en KW - Cough KW - Diarrhea KW - Dyspnea KW - EGFR KW - Pain KW - Afatinib KW - Antineoplastic Combined Chemotherapy Protocols KW - Carcinoma, Squamous Cell KW - Erlotinib Hydrochloride KW - Female KW - Humans KW - Lung Neoplasms KW - Male KW - Middle Aged KW - Neoplasm Staging KW - Patient Reported Outcome Measures KW - Platinum Compounds KW - Quality of Life KW - Survival Analysis TI - Symptom and Quality of Life Improvement in LUX-Lung 8, an Open-Label Phase III Study of Second-Line Afatinib Versus Erlotinib in Patients With Advanced Squamous Cell Carcinoma of the Lung After First-Line Platinum-Based Chemotherapy. TY - research article VL - 19 ER -