RT Journal Article T1 Effect of Periodic Vehicle Inspection on Road Crashes and Injuries: A Systematic Review A1 Martín-delosReyes, Luis Miguel A1 Lardelli-Claret, Pablo A1 García-Cuerva, Laura A1 Rivera-Izquierdo, Mario A1 Jiménez-Mejías, Eladio A1 Martínez-Ruiz, Virginia K1 Vehicle inspection K1 Road crash K1 Road injury K1 Motor vehicles K1 Vehículos a motor K1 Inspección de vehículos K1 Accidente de tráfico K1 Estudios de cohortes AB This systematic review was conducted to determine the effect of periodic motor vehicle inspections on road crashes and injuries, compared to less exposure to periodic inspections or no inspections. The Medline, Web of Science, and Scopus databases were used to search the literature. Ecological studies were specifically excluded. A reverse search of the results with these databases and of other identified narrative reviews was also performed. Of the 5065 unique references initially extracted, only six of them met the inclusion criteria and were selected for review: one experimental study, two cohort studies with an internal comparison group, two cohort studies without a comparison group, and one case-control study. Two authors independently extracted the information and assessed the quality of each study. Due to the heterogeneity of the designs and the intervention or comparison groups used, quantitative synthesis of the results was not attempted. Except for the case-control study, which showed a significant association between road crashes and the absence of a valid vehicle inspection certificate, the other studies showed either a small reduction in crash rates (around 9%), no association, or a higher crash rate in vehicles with more inspections. In all observational studies, the risk of residual confounding bias was significant and could have explained the results. Therefore, although the research reviewed here suggests that periodic inspection may be associated with a slight reduction in road crashes, the marked heterogeneity along with probable residual confounding in most reports prevented us from establishing causality for this association. PB MDPI YR 2021 FD 2021-06-15 LK http://hdl.handle.net/10668/3953 UL http://hdl.handle.net/10668/3953 LA en NO Martín-delosReyes LM, Lardelli-Claret P, García-Cuerva L, Rivera-Izquierdo M, Jiménez-Mejías E, Martínez-Ruiz V. Effect of Periodic Vehicle Inspection on Road Crashes and Injuries: A Systematic Review. Int J Environ Res Public Health. 2021 Jun 15;18(12):6476. DS RISalud RD Apr 15, 2025