TY - JOUR AU - de Oliveira, Jade AU - Kucharska, Ewa AU - Garcez, Michelle Lima AU - Rodrigues, Matheus Scarpatto AU - Quevedo, João AU - Moreno-Gonzalez, Ines AU - Budni, Josiane PY - 2021 DO - 10.3390/cells10102581 UR - http://hdl.handle.net/10668/3613 T2 - Cells AB - Alzheimer's disease (AD) is the leading cause of dementia worldwide. Most AD patients develop the disease in late life, named late onset AD (LOAD). Currently, the most recognized explanation for AD pathology is the amyloid cascade hypothesis. It is... LA - en PB - MDPI KW - Alzheimer’s disease KW - Neurodegenerative disease KW - Dementia KW - Neuroinflammation KW - Inflammatory cascade KW - Systemic inflammation KW - BBB disruption KW - Anti-inflammatory effects KW - Therapy KW - Enfermedad de Alzheimer KW - Enfermedades neurodegenerativas KW - Demencia KW - Terapéutica KW - Síndrome de respuesta inflamatoria sistémica KW - Medical Subject Headings::Persons::Persons::Age Groups::Adult::Aged KW - Medical Subject Headings::Diseases::Nervous System Diseases::Central Nervous System Diseases::Brain Diseases::Dementia::Alzheimer Disease KW - Medical Subject Headings::Organisms::Eukaryota::Animals KW - Medical Subject Headings::Diseases::Animal Diseases::Disease Models, Animal KW - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Death KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans KW - Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Antirheumatic Agents KW - Medical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Inflammation::Systemic Inflammatory Response Syndrome TI - Inflammatory Cascade in Alzheimer's Disease Pathogenesis: A Review of Experimental Findings TY - review article ER -