TY - JOUR AU - Wu, Ying-Yu AU - Kumar, Ramesh AU - Iida, Ryuji AU - Bagavant, Harini AU - Alarcón-Riquelme, Marta E PY - 2016 DO - 10.1371/journal.pone.0156302 UR - http://hdl.handle.net/10668/10124 T2 - PloS one AB - The purpose of our study was to investigate the effects of the adaptor Bank1 in TLR7 signaling using the B6.Sle1.yaa mouse, a lupus model that develops disease through exacerbated TLR7 expression. Crosses of B6.Sle1.yaa with Bank1-/- mice maintained... LA - en KW - Adaptor Proteins, Signal Transducing KW - Animals KW - Autoantibodies KW - B-Lymphocytes KW - Cells, Cultured KW - Female KW - Immunoglobulin G KW - Interleukin-6 KW - Lupus Erythematosus, Systemic KW - Male KW - Membrane Glycoproteins KW - Mice KW - Mice, Inbred C57BL KW - Mice, Knockout KW - Phenotype KW - STAT1 Transcription Factor KW - Toll-Like Receptor 7 TI - BANK1 Regulates IgG Production in a Lupus Model by Controlling TLR7-Dependent STAT1 Activation. TY - research article VL - 11 ER -