TY - JOUR AU - Entrenas Castillo, Marta AU - Entrenas Costa, Luis Manuel AU - Vaquero Barrios, Jose Manuel AU - Alcala Diaz, Juan Francisco AU - Lopez Miranda, Jose AU - Bouillon, Roger AU - Quesada Gomez, Jose Manuel PY - 2020 DO - 10.1016/j.jsbmb.2020.105751 UR - http://hdl.handle.net/10668/16186 T2 - The Journal of steroid biochemistry and molecular biology AB - The vitamin D endocrine system may have a variety of actions on cells and tissues involved in COVID-19 progression especially by decreasing the Acute Respiratory Distress Syndrome. Calcifediol can rapidly increase serum 25OHD concentration. We... LA - en KW - 1α, 25(OH)2D or 1α, 25-dihydroxyvitamin D or calcitriol KW - Acute respiratory distress syndrome (ARDS) KW - COVID-19 KW - Calcifediol or 25-hydroxyvitamin D3 KW - Cathelicidin peptide KW - Chloroquine KW - Covidiol KW - Cuboidal alveolar coating cells type II KW - Cytokine/Chemokine storm KW - Defensins KW - Hydroxychloroquine KW - Hypercoagulability KW - Neutrophil activity KW - Renin-angiotensin system KW - SARS-CoV-2 KW - TLR co-receptor CD14 KW - Vitamin D KW - Vitamin D endocrine system KW - Vitamin D receptor KW - Vitamin D3 or cholecalciferol KW - Betacoronavirus KW - Bone density conservation agents KW - COVID-19 KW - Calcifediol KW - Coronavirus infections KW - Double-blind method KW - Female KW - Hospitalization KW - Humans KW - Intensive care units KW - Male KW - Middle aged KW - Pandemics KW - Pilot projects KW - Pneumonia, viral KW - Prognosis KW - SARS-CoV-2 TI - "Effect of calcifediol treatment and best available therapy versus best available therapy on intensive care unit admission and mortality among patients hospitalized for COVID-19: A pilot randomized clinical study". TY - research article VL - 203 ER -