RT Journal Article
T1 A 2-year follow-up of a novel Fracture Liaison Service: can we reduce the mortality in elderly hip fracture patients? A prospective cohort study.
A1 Gonzalez-Quevedo, David
A1 Perez-Del-Rio, V
A1 Moriel-Garceso, D
A1 Fernandez-Arroyabe, N
A1 Garcia-Melendez, G
A1 Montañez-Ruiz, M
A1 Bravo-Bardaji, M
A1 Garcia-de-Quevedo, D
A1 Tamimi, I
K1 Fracture Liaison Service
K1 Hip fractures
K1 Mortality
K1 Osteoporosis
K1 Re-fracture
K1 Survival
AB Osteoporosis is an underdiagnosed disease that results in bone fragility and risk of fractures. Fracture Liaison Service (FLS) is a secondary prevention model which identifies patients at risk for fragility fractures. The introduction of a FLS protocol showed an increase of anti-osteoporotic drug prescription and significant reduction of all-cause mortality. Hip fractures are the most severe osteoporotic fracture due to their associated disability and elevated risk of mortality. FLS programs have enhanced the management of osteoporosis-related fractures. Our objective is to analyze the effect of the FLS model over survival and 2-year mortality rate following a hip fracture. We conducted a prospective cohort study on patients over 60 years of age who suffered a hip fracture during 3 consecutive years, before and after the implementation of the FLS in our center (i.e., between January 2016 and December 2018). Patients' information was withdrawn from our local computerized database. Patients were followed for 2 years after the hip fracture. Mortality and re-fracture rates were compared between the two groups using a multivariate Cox proportional hazard model. A total of 1101 patients were included in this study (i.e., 357 before FLS implementation and 744 after FLS implementation). Anti-osteoporotic drugs were more frequently prescribed after FLS implementation (583 (78.4%) vs 44 (12.3%); p  The implementation of a FLS protocol was associated with an increase of anti-osteoporotic treatment, higher adherence, and greater survival in elderly hip fracture patients. There was a significant reduction of all-cause mortality in the FLS patients treated with anti-osteoporotic. However, the application of the FLS did not affect the risk of suffering a second fragility fracture.
PB Springer
YR 2022
FD 2022-03-31
LK http://hdl.handle.net/10668/19620
UL http://hdl.handle.net/10668/19620
LA en
NO González-Quevedo D, Pérez-Del-Río V, Moriel-Garceso D, Fernández-Arroyabe N, García-Meléndez G, Montañez-Ruiz M, et al. A 2-year follow-up of a novel Fracture Liaison Service: can we reduce the mortality in elderly hip fracture patients? A prospective cohort study. Osteoporos Int. 2022 Aug;33(8):1695-1702
DS RISalud
RD Apr 7, 2025