RT Journal Article T1 Crohn's disease and cystic fibrosis: there is still a lot to learn. A1 Trigo Salado, Claudio A1 Leo Carnerero, Eduardo A1 de la Cruz Ramírez, María Dolores AB The relationship between cystic fibrosis (CF) and the risk of developing inflammatory bowel disease (IBD) is not clear. CFTR mutations can influence dysbiosis and increased intestinal permeability, which are two key elements in the pathophysiology of IBD. These patients have increased intestinal inflammation, as demonstrated by increase pro-inflammatory gene expression in the bowel, specific fecal markers (fecal calprotectin), gross lesions (capsule endoscopy) and histological lesions on examination of surgical specimens. SN 1130-0108 YR 2018 FD 2018 LK http://hdl.handle.net/10668/12973 UL http://hdl.handle.net/10668/12973 LA en DS RISalud RD Apr 11, 2025