TY - JOUR AU - Ulzurrun, Eugenia AU - Stephens, Camilla AU - Ruiz-Cabello, Francisco AU - Robles-Díaz, Mercedes AU - Sáenz-López, Pablo AU - Hallal, Hacibe AU - Soriano, Germán AU - Román, Eva AU - Fernández, M Carmen AU - Lucena, M Isabel AU - Andrade, Raúl J PY - 2014 DO - 10.1371/journal.pone.0094675 UR - http://hdl.handle.net/10668/1628 T2 - PloS One AB - BACKGROUND AND AIMSFlawed ABC transporter functions may contribute to increased risk of drug-induced liver injury (DILI). We aimed to analyse the influence of genetic variations in ABC transporters on the risk of DILI development and clinical... LA - en PB - Public Library of Science KW - Alelos KW - Polimorfismo Genético KW - Transportadoras de Casetes de Unión a ATP KW - Proteínas Asociadas a Resistencia a Múltiples Medicamentos KW - Enfermedad Hepática Inducida por Drogas KW - Haplotipos KW - España KW - Bilirrubina KW - Estudios Epidemiológicos KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Variation::Polymorphism, Genetic KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Structures::Genome::Genome Components::Genes::Alleles KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Membrane Proteins::Membrane Transport Proteins::ATP-Binding Cassette Transporters KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Membrane Proteins::Membrane Transport Proteins::ATP-Binding Cassette Transporters::Multidrug Resistance-Associated Proteins KW - Medical Subject Headings::Diseases::Substance-Related Disorders::Poisoning::Drug-Induced Liver Injury KW - Medical Subject Headings::Geographicals::Geographic Locations::Europe::Spain KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genotype::Haplotypes KW - Medical Subject Headings::Chemicals and Drugs::Biological Factors::Pigments, Biological::Bile Pigments::Bilirubin KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies TI - Selected ABCB1, ABCB4 and ABCC2 Polymorphisms Do Not Enhance the Risk of Drug-Induced Hepatotoxicity in a Spanish Cohort. TY - research article ER -