RT Journal Article T1 Social economic costs of type 1 diabetes mellitus in pediatric patients in Spain: CHRYSTAL observational study. A1 López-Bastida, Julio A1 López-Siguero, Juan Pedro A1 Oliva-Moreno, Juan A1 Perez-Nieves, Magaly A1 Villoro, Renata A1 Dilla, Tatiana A1 Merino, María A1 Jiang, Dingfeng A1 Aranda-Reneo, Isaac A1 Reviriego, Jesús A1 Vázquez, Luis Alberto K1 Costs studies K1 Pediatric population K1 Social costs K1 Type 1 diabetes mellitus AB To estimate the social-economic costs of Type 1 Diabetes Mellitus (T1DM) in patients aged 0-17years in Spain from a social perspective. We conducted a cross-sectional observational study in 2014 of 275 T1DM pediatric outpatients distributed across 12 public health centers in Spain. Data on demographic and clinical characteristics, healthcare utilization and informal care were collected from medical records and questionnaires completed by clinicians and patients' caregivers. A valid sample of 249 individuals was analyzed. The average annual cost for a T1DM patient was €27,274. Direct healthcare costs were €4070 and direct non-healthcare cost were €23,204. Informal (familial) care represented 83% of total cost, followed by medical material (8%), outpatient and primary care visits (3.1%) and insulin (2.1%). Direct healthcare cost per patient statistically differed by glycated haemoglobin (HbA1c) level [mean cost €4704 in HbA1c ≥7.5% (≥58mmol/mol) group vs. €3616 in HbA1c T1DM amongst pediatric patients incurs in considerable societal costs. Informal care represents the largest cost category. YR 2017 FD 2017-03-07 LK http://hdl.handle.net/10668/10979 UL http://hdl.handle.net/10668/10979 LA en DS RISalud RD Apr 9, 2025