RT Journal Article
T1 Thyroid metastasis as initial presentation of clear cell renal carcinoma.
A1 Ramírez-Plaza, César Pablo
A1 Domínguez-López, Marta Elena
A1 Blanco-Reina, Francisco
K1 Carcinoma
K1 Metastasis
K1 Renal
K1 Thyroid
K1 Treatment
K1 Biopsia
K1 Carcinoma de células renales
K1 Estudios de seguimiento
K1 Bocio
K1 Neoplasias renales
K1 Nefrectomía
K1 Neoplasias de la tiroides
K1 Nódulo tiroideo
K1 Tiroidectomía
K1 Tomografía computarizada por rayos X
K1 Vacuolas
AB INTRODUCTIONMetastatic tumors account for 1.4-2.5% of thyroid malignancies. About 25-30% of patients with clear cell renal carcinoma (CCRC) have distant metastasis at the time of diagnosis, being the thyroid gland a rare localization [5%].PRESENTATION OF THE CASEA 62-year woman who underwent a cervical ultrasonography and a PAAF biopsy reporting atypical follicular proliferation with a few intranuclear vacuoles "suggestive" of thyroid papillary cancer in the context of a multinodular goiter was reported. A total thyroidectomy was performed and the histology of a clear cell renal carcinoma (CCRC) was described in four nodules of the thyroid gland. A CT scan was performed and a renal giant right tumor was found. The patient underwent an eventful radical right nephrectomy and the diagnosis of CCRC was confirmed.DISCUSSIONThyroid metastasis (TM) from CCRC are usually apparent in a metachronic context during the follow-up of a treated primary (even many years after) but may sometimes be present at the same time than the primary renal tumor. Our case is exceptional because the TM was the first evidence of the CCRC, which was subsequently diagnosed and treated.CONCLUSIONThe possibility of finding of an incidental metastatic tumor in the thyroid gland from a previous unknown and non-diganosed primary (as CCRC in our case was) is rare and account only for less than 1% of malignancies. Nonetheless, the thyroid gland is a frequent site of metastasis and the presence of "de novo" thyroid nodules in oncologic patients must be always considered and studied.
PB Elsevier
YR 2015
FD 2015
LK http://hdl.handle.net/10668/2192
UL http://hdl.handle.net/10668/2192
LA en
NO Ramírez-Plaza CP, Domínguez-López ME, Blanco-Reina F. Thyroid metastasis as initial presentation of clear cell renal carcinoma. Int J Surg Case Rep. 2015; 10:101-3
NO Journal Article;
DS RISalud
RD Apr 19, 2025