RT Journal Article T1 Epidermal Barrier Function and Skin Homeostasis in Skin with Permanent and Adhesive Tattoos: A Cross-Sectional Study. A1 Serrano-Serra, Jose-Pablo A1 Montero-Vilchez, Trinidad A1 Buendia-Eisman, Agustin A1 Arias-Santiago, Salvador K1 adhesives K1 antioxidants K1 epidermis K1 petrolatum K1 skin barrier K1 tattooing AB Tattoos are a current trend, but their impact on skin homeostasis and epidermal barrier function is not well known. So, the aims of this study are (1) to investigate epidermal barrier function and skin homeostasis in skin with permanent tattoos, adhesive temporary tattoos and non-tattooed skin, and (2) to analyze the effect of petrolatum on skin with permanent and adhesive tattoos. In total, 67 tattoos were enrolled (34 permanent tattoos and 33 adhesive tattoos). Temperature, transepidermal water loss (TEWL), stratum corneum hydration (SCH), erythema and total antioxidant capacity (TAC) were measured in skin with permanent tattoos, adhesive tattoos and non-tattooed skin before and after petrolatum application. The temperature was lower (30.47 °C vs. 31.01 °C; p = 0.001) on skin with permanent tattoos than non-tattooed skin, while SCH (48.24 Arbitrary Units (AU) vs. 44.15 AU; p = 0.008) was higher. Skin with adhesive tattoos showed lower temperature, SCH (21.19 AU vs. 41.31 AU; p PB MDPI AG SN 2077-0383 YR 2021 FD 2021-02-14 LK http://hdl.handle.net/10668/17297 UL http://hdl.handle.net/10668/17297 LA en NO Serrano-Serra JP, Montero-Vilchez T, Buendia-Eisman A, Arias-Santiago S. Epidermal Barrier Function and Skin Homeostasis in Skin with Permanent and Adhesive Tattoos: A Cross-Sectional Study. J Clin Med. 2021 Feb 22;10(4):888. DS RISalud RD Apr 5, 2025