RT Journal Article
T1 Mycobacterium tuberculosis Acquires Limited Genetic Diversity in Prolonged Infections, Reactivations and Transmissions Involving Multiple Hosts
A1 Herranz, Marta
A1 Pole, Ilva
A1 Ozere, Iveta
A1 Chiner-Oms, Alvaro
A1 Martinez-Lirola, Miguel
A1 Perez-Garcia, Felipe
A1 Gijon, Paloma
A1 Ruiz Serrano, Maria Jesus
A1 Clotet Romero, Laura
A1 Cuevas, Oscar
A1 Comas, Inaki
A1 Bouza, Emilio
A1 Perez-Lago, Laura
A1 Garcia-de-Viedma, Dario
K1 tuberculosis
K1 variability
K1 whole genome sequencing
K1 SNPs
K1 microevolution
K1 Clonal variants
K1 Microevolution
K1 Outbreaks
K1 Strain
K1 Africa
AB Background: Mycobacterium tuberculosis (MTB) has limited ability to acquire variability. Analysis of its microevolution might help us to evaluate the pathways followed to acquire greater infective success. Whole-genome sequencing (WGS) in the analysis of the transmission of MTB has elucidated the magnitude of variability in MTB. Analysis of transmission currently depends on the identification of clusters, according to the threshold of variability (
PB Frontiers media sa
SN 1664-302X
YR 2018
FD 2018-01-19
LK http://hdl.handle.net/10668/19225
UL http://hdl.handle.net/10668/19225
LA en
DS RISalud
RD Apr 11, 2025