RT Journal Article
T1 Editorial: Systems Biology Approach to the Immunology of Asthma and Allergy.
A1 Karaaslan, Cagatay
A1 Mayorga, Cristobalina
A1 Baerenfaller, Katja
A1 Escribese, Maria M
K1 Allergy
K1 Asthma
K1 Biomarker
K1 Immunology
K1 System biology
AB Theprevalence of allergic diseases as well as their severity have risen progressively during the last decades, affecting a considerable percentage of the population worldwide. Asthma and allergies as a whole are heterogeneous and show acomplexpatternof disease endotypes, a complicated balance between immune tolerance and allergic sensitization, and a progression of allergic diseases. The application of highthroughput technologies enables the profiling of genomes, epigenomes, transcriptomes, microbiomes and metabolomestogainabetter understandingoftheimmunemechanismsunderlyingasthmaandallergies. The use of systems biology aims at combining and connecting the information on the different molecular components on the cell, tissue, or organ level to discover the properties of the full system. A system’s level understanding of the complex allergic diseases will then assist in implementing personalized medicine strategies for the treatment of allergic and asthmatic patients.
YR 2022
FD 2022-02-14
LK http://hdl.handle.net/10668/20581
UL http://hdl.handle.net/10668/20581
LA en
NO Karaaslan C, Mayorga C, Baerenfaller K, Escribese MM. Editorial: Systems Biology Approach to the Immunology of Asthma and Allergy. Front Immunol. 2022 Feb 14;13:857403
NO This work was supported by ISCIII (PI18/01467), cofounded by FEDER “Investing in your future” for the thematic network and co-operative research centres ARADyAL RD16/0006/0015; as well as by the grant from Ministerio de Ciencia, Innovación y Universidades co-financed with FEDER RTI2018-095166-B-I00.
DS RISalud
RD Apr 4, 2025